The acellular pertussis vaccine component is produced by biken tanabe corporation osaka japan and is combined with diphtheria and tetanus toxoids manufactured by connaught laboratories inc diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed prepared and distributed as infanrix tm was licensed january 29 1997. Acellular pertussis vaccines coordinated efforts on the part of manufacturers research institutions and national regulatory authorities have led to the development of a variety of acellular pertussis vaccines that appear to be effective in clinical studies. T he prospect of a new acellular pertussis vaccine has been a hot topic of discussion by both the canadian paediatric societys immunization and infectious disease committee and the national advisory committee on immunization for a number of years this promise of a new improved vaccine with less side effects being just around the corner has been circulating for over five years
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